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BIOCOMP
2010
13 years 6 months ago
Using the Genetic Code Wisdom for Recognizing Protein Coding Sequences
We have elaborated a new method of recognizing protein coding sequences in genomic sequences. The method is exploiting a specific way of genetic code degeneration and relations bet...
Pawel Blazej, Pawel Mackiewicz, Stanislaw Cebrat
BIOCOMP
2010
13 years 6 months ago
A Network-based Approach to Classify Disease Stages of Prostate Cancer Using Quantitative Network Measures
Abstract-- This study deals with investigating the classification performance of information-theoretic measures when applied to complex biological networks. In particular, our aim ...
Laurin A. J. Mueller, Karl G. Kugler, Andreas Dand...
BIOCOMP
2010
13 years 7 months ago
Robust Stability Analysis and Design Under Consideration of Multiple Feedback Loops in the Tryptophan Regulatory Network of E. c
The tryptophan operon of E. coli represents an important regulatory unit consisting of multiple feedback loops. The role of these loops is crucial to understand the dynamics of tr...
Anke Meyer-Bäse, Fabian J. Theis
BIOCOMP
2010
13 years 7 months ago
A Hierarchical Decision Engine for Computer Aided Lung Nodule Detection from CT Images
- We present a novel hierarchical modular decision engine for lung nodule detection from CT images implemented by Artificial Neural Networks. The proposed Computer Aided Detection ...
Ömer M. Soysal, Jianhua Chen, Steven Bujenovi...
BIOCOMP
2010
13 years 7 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BIOCOMP
2010
13 years 7 months ago
Extraction of Protein Sequence Motifs Information by Bi-Clustering Algorithm
- The activities and function of proteins can potentially be determined by protein sequence motifs. Therefore, obtaining the universally conserved and crossed protein family bounda...
Vincent Yip, Bernard Chen, Sinan Kockara
BIOCOMP
2010
13 years 7 months ago
Intrinsic Contact Geometry of Protein Dynamics
Yosi Shibberu, Mark Brandt, David Cooper