BMCBI
2006
13 years 5 months ago
2006
Background: The genome sequencing projects have shown our limited knowledge regarding gene function, e.g. S. cerevisiae has 5
BMCBI
2006
13 years 5 months ago
2006
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
BMCBI
2006
13 years 5 months ago
2006
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
BMCBI
2006
13 years 5 months ago
2006
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
BMCBI
2006
13 years 5 months ago
2006
Background: Bacterial typing schemes based on the sequences of genes encoding surface antigens require databases that provide a uniform, curated, and widely accepted nomenclature ...
BMCBI
2006
13 years 5 months ago
2006
Background: The invariant lineage of the nematode Caenorhabditis elegans has potential as a powerful tool for the description of mutant phenotypes and gene expression patterns. We...
BMCBI
2006
13 years 5 months ago
2006
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
BMCBI
2006
13 years 5 months ago
2006
Background: Molecular maps have been developed for many species, and are of particular importance for varietal development and comparative genomics. However, despite the existence...
BMCBI
2006
13 years 5 months ago
2006
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...
BMCBI
2006
13 years 5 months ago
2006
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...