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BMCBI
2010
163views more  BMCBI 2010»
8 years 3 months ago
RISCI - Repeat Induced Sequence Changes Identifier: a comprehensive, comparative genomics-based, in silico subtractive hybridiza
Background -: The availability of multiple whole genome sequences has facilitated in silico identification of fixed and polymorphic transposable elements (TE). Whereas polymorphic...
Vipin Singh, Rakesh K. Mishra
BMCBI
2010
219views more  BMCBI 2010»
8 years 3 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
BMCBI
2010
195views more  BMCBI 2010»
8 years 3 months ago
MBAT: A scalable informatics system for unifying digital atlasing workflows
Background: Digital atlases provide a common semantic and spatial coordinate system that can be leveraged to compare, contrast, and correlate data from disparate sources. As the q...
Daren Lee, Seth Ruffins, Queenie Ng, Nikhil Sane, ...
BMCBI
2010
179views more  BMCBI 2010»
8 years 3 months ago
Circadian signatures in rat liver: from gene expression to pathways
Background: Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is ent...
Meric A. Ovacik, Siddharth Sukumaran, Richard R. A...
BMCBI
2010
144views more  BMCBI 2010»
8 years 3 months ago
Optimizing Transformations for Automated, High Throughput Analysis of Flow Cytometry Data
Background: In a high throughput setting, effective flow cytometry data analysis depends heavily on proper data preprocessing. While usual preprocessing steps of quality assessmen...
Greg Finak, Juan-Manuel Perez, Andrew Weng, Raphae...
BMCBI
2010
216views more  BMCBI 2010»
8 years 3 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2010
223views more  BMCBI 2010»
8 years 3 months ago
MetNetGE: interactive views of biological networks and ontologies
Background: Linking high-throughput experimental data with biological networks is a key step for understanding complex biological systems. Currently, visualization tools for large...
Ming Jia, Suh-Yeon Choi, Dirk Reiners, Eve Syrkin ...
BMCBI
2010
185views more  BMCBI 2010»
8 years 3 months ago
MetaPIGA v2.0: maximum likelihood large phylogeny estimation using the metapopulation genetic algorithm and other stochastic heu
Background: The development, in the last decade, of stochastic heuristics implemented in robust application softwares has made large phylogeny inference a key step in most compara...
Raphaël Helaers, Michel C. Milinkovitch
BMCBI
2010
104views more  BMCBI 2010»
8 years 3 months ago
A systematic study of genome context methods: calibration, normalization and combination
Background: Genome context methods have been introduced in the last decade as automatic methods to predict functional relatedness between genes in a target genome using the patter...
Luciana Ferrer, Joseph M. Dale, Peter D. Karp
BMCBI
2010
172views more  BMCBI 2010»
8 years 3 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
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