BMCBI
2010
13 years 4 months ago
2010
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
BMCBI
2010
13 years 4 months ago
2010
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
BMCBI
2010
13 years 4 months ago
2010
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
BMCBI
2010
13 years 4 months ago
2010
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
BMCBI
2010
13 years 4 months ago
2010
Background: The system-level dynamics of many molecular interactions, particularly protein-protein interactions, can be conveniently represented using reaction rules, which can be...
BMCBI
2010
13 years 4 months ago
2010
BMCBI
2010
13 years 4 months ago
2010
BMCBI
2010
13 years 4 months ago
2010
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
BMCBI
2010
13 years 4 months ago
2010
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...