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CANDC
2005
ACM
12 years 1 months ago
Haplotype assembly from aligned weighted SNP fragments
Given an assembled genome of a diploid organism the haplotype assembly problem can be formulated as retrieval of a pair of haplotypes from a set of aligned weighted SNP fragments....
Yu-Ying Zhao, Ling-Yun Wu, Ji-Hong Zhang, Rui-Shen...
CANDC
2005
ACM
12 years 1 months ago
MSAID: multiple sequence alignment based on a measure of information discrepancy
We propose an algorithm of global multiple sequence alignment that is based on a measure of what we call information discrepancy. The algorithm follows a progressive alignment ite...
Min Zhang, Weiwu Fang, Junhua Zhang, Zhongxian Chi
CANDC
2005
ACM
12 years 1 months ago
Integer linear programming as a tool for constructing trees from quartet data
The task of the quartet puzzling problem is to find a best-fitting binary X-tree for a finite n-set from confidence values for the 3 n 4 binary trees with exactly four leaves from...
Jan Weyer-Menkhoff, Claudine Devauchelle, Alexande...
CANDC
2005
ACM
12 years 1 months ago
Gene selection from microarray data for cancer classification - a machine learning approach
A DNA microarray can track the expression levels of thousands of genes simultaneously. Previous research has demonstrated that this technology can be useful in the classification ...
Yu Wang 0008, Igor V. Tetko, Mark A. Hall, Eibe Fr...
CANDC
2005
ACM
12 years 1 months ago
Assessment of chemical libraries for their druggability
High throughput virtual screening is acknowledged as the initial means for identifying hit compounds that will be eventually transformed to leads or drug candidates. To improve qu...
Suzanne W. Sirois, George Hatzakis, Dongqing Wei, ...
CANDC
2005
ACM
12 years 1 months ago
A family of metrics for biopolymers based on counting independent sets
We introduce a new family of metrics for graphs of fixed size, based on counting-independent sets. Our definition is simpler and easier to e than the edge ideal metric family defi...
Jairo Rocha, Mercè Llabrés, Ricardo ...
CANDC
2005
ACM
12 years 1 months ago
Comments on selected fundamental aspects of microarray analysis
Microarrays are becoming a ubiquitous tool of research in life sciences. However, the working principles of microarray-based methodologies are often misunderstood or apparently ig...
Alessandra Riva, Anne-Sophie Carpentier, Bruno Tor...
CANDC
2005
ACM
12 years 1 months ago
Overlapping genes in vertebrate genomes
Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can ...
Izabela Makalowska, Chiao-Feng Lin, Wojciech Makal...
CANDC
2005
ACM
12 years 1 months ago
Latent periodicity of serine-threonine and tyrosine protein kinases and other protein families
We identified latent periodicity in catalytic domains of approximately 85% of annotated serine
Andrew A. Laskin, Nikolay A. Kudryashov, Konstanti...
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