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PRIB
2010
Springer
192views Bioinformatics» more  PRIB 2010»
8 years 6 months ago
Structured Output Prediction of Anti-cancer Drug Activity
We present a structured output prediction approach for classifying potential anti-cancer drugs. Our QSAR model takes as input a description of a molecule and predicts the activity...
Hongyu Su, Markus Heinonen, Juho Rousu
BMCBI
2005
118views more  BMCBI 2005»
8 years 8 months ago
Feature selection and classification for microarray data analysis: Evolutionary methods for identifying predictive genes
Background: In the clinical context, samples assayed by microarray are often classified by cell line or tumour type and it is of interest to discover a set of genes that can be us...
Thanyaluk Jirapech-Umpai, J. Stuart Aitken
BMCBI
2007
157views more  BMCBI 2007»
8 years 8 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
ISBI
2009
IEEE
9 years 3 months ago
Morphometric Subtyping for a Panel of Breast Cancer Cell Lines
A panel of cell lines of diverse molecular background offers an improved model system for high-content screening, comparative analysis, and cell systems biology. A computational p...
Ju Han, Hang Chang, Gerald Fontenay, Nicholas J. W...
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