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GCB
2007
Springer
83views Biometrics» more  GCB 2007»
11 years 9 months ago
Supervised Posteriors for DNA-motif Classification
: Markov models have been proposed for the classification of DNA-motifs using generative approaches for parameter learning. Here, we propose to apply the discriminative paradigm fo...
Jan Grau, Jens Keilwagen, Alexander E. Kel, Ivo Gr...
GCB
2007
Springer
91views Biometrics» more  GCB 2007»
11 years 11 months ago
Integrative Analysis of Transcriptome and Metabolome Data
Biological systems have to react to environmental and/or developmental changes by adjusting their biochemical/cellular machinery on numerous levels. In many cases small molecules ...
Lothar Willmitzer, Camila Caldana, Alisdair R. Fer...
GCB
2007
Springer
134views Biometrics» more  GCB 2007»
11 years 11 months ago
An Application of Latent Topic Document Analysis to Large-Scale Proteomics Databases
Since the advent of public data repositories for proteomics data, readily accessible results from high-throughput experiments have been accumulating steadily. Several large-scale p...
Sebastian Klie, Lennart Martens, Juan Antonio Vizc...
GCB
2007
Springer
91views Biometrics» more  GCB 2007»
11 years 11 months ago
A Study on the Empirical Support for Prior Distributions on Phylogenetic Tree Topologies
: There are several models for the evolutionary process forming a species tree. We examine the Birth-and-Death model (BDM), the Proportional-to-Distinguishable Arrangements (PDA) m...
Lin Himmelmann, Dirk Metzler
GCB
2007
Springer
89views Biometrics» more  GCB 2007»
11 years 11 months ago
Expected Gene Order Distances and Model Selection in Bacteria
The most parsimonous distances calculated in pairwise gene order comparisons cannot accurately reflect the true number of events separating two species, unless the number of chan...
Niklas Eriksen
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
11 years 11 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
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