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CIBCB
2007
IEEE
13 years 6 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...
EPIA
2007
Springer
13 years 10 months ago
Evaluating Simulated Annealing Algorithms in the Optimization of Bacterial Strains
Abstract. In this work, a Simulated Annealing (SA) algorithm is proposed for a Metabolic Engineering task: the optimization of the set of gene deletions to apply to a microbial str...
Miguel Rocha, Rui Mendes, Paulo Maia, José ...