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TCBB
2011
10 years 8 months ago
Semi-Markov Models for Brownian Dynamics Permeation in Biological Ion Channels
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
Vikram Krishnamurthy, Kai Yiu Luk
JCNS
2002
62views more  JCNS 2002»
11 years 1 months ago
Computing Transient Gating Charge Movement of Voltage-Dependent Ion Channels
The opening of voltage-gated sodium, potassium, and calcium ion channels has a steep relationship with voltage. In response to changes in the transmembrane voltage, structural move...
Anthony Varghese, Linda M. Boland
ISCAS
2006
IEEE
133views Hardware» more  ISCAS 2006»
11 years 7 months ago
Neuronal ion-channel dynamics in silicon
Abstract— We present a simple silicon circuit for modelling voltagedependent ion channels found within neural cells, capturing both the gating particle’s sigmoidal activation (...
Kai M. Hynna, Kwabena Boahen
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