Sciweavers

ISMB
1993
13 years 5 months ago
Identification of Localized and Distributed Bottlenecks in Metabolic Pathways
The usual thermodynamicevaluation, based solely on the Standard Gibbs Energyof reaction, does not take into account the permissible ranges of concentrations of metabolites, and it...
Michael L. Mavrovouniotis
ISMB
1993
13 years 5 months ago
MultiMap: An Expert System for Automated Genetic Linkage Mapping
Withthe advent of the HumanGenomeProject. the ability to rapidly construct comprehensiveand accuratelinkage mapsbasedongenetic markerdata fromfamily studies is an absolute necessi...
Tara Cox Matise, Mark Perlin, Aravinda Chakravarti
ISMB
1993
13 years 5 months ago
Design of an Object-Oriented Database for Reverse Genetics
Krys Kochut, Jonathan Arnold, John A. Miller, Walt...
ISMB
1993
13 years 5 months ago
Detection of Correlations in tRNA Sequences with Structural Implications
Using a flexible representation of biological sequences, we have performed a comparative analysis of 1208 known tRNA sequences. We believe we our technique is a more sensitive met...
Tod M. Klingler, Douglas L. Brutlag
ISMB
1993
13 years 5 months ago
Protein Sequencing Experiment Planning Using Analogy
Experiment design and execution is a central activity in the natural sciences. The SeqERsystem provides a general architecture for the integration of automated planning techniques...
Brian P. Kettler, Lindley Darden
ISMB
1993
13 years 5 months ago
Representations of Metabolic Knowledge
Construction of electronic repositories of metabolic information is an increasingly active area of research. Encoding detailed knowledge of a complex biological domain requires ï¬...
Peter D. Karp, Monica Riley
ISMB
1993
13 years 5 months ago
A Modular Learning Environment for Protein Modeling
Wepropose in this paper a modularlearning environmentfor proteinmodeling.In this system,the protein modelingproblemis tackledin twosuccessive phases. First, partial structural inf...
Jérôme Gracy, Laurent Chiche, Jean Sa...
ISMB
1993
13 years 5 months ago
Finding Relevant Biomolecular Features
Manymethods for analyzing biological problems are constrained by problemsize. Theability to distinguish betweenrelevant andirrelevant features of a problemmay allowa problemto be ...
Lawrence Hunter, Teri E. Klein