BMCBI
2008
13 years 4 months ago
2008
Background: In DNA microarray gene expression profiling studies, a fundamental task is to extract statistically significant genes that meet certain research hypothesis. Currently,...
BMCBI
2008
13 years 4 months ago
2008
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
BMCBI
2008
13 years 4 months ago
2008
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
BMCBI
2007
13 years 4 months ago
2007
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
BMCBI
2007
13 years 4 months ago
2007
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
BMCBI
2010
13 years 5 months ago
2010
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
HCI
2007
13 years 6 months ago
2007
Efficient and effective analysis of large datasets from microarray gene expression data is one of the keys to time-critical personalized medicine. The issue we address here is the ...
BIBE
2004
IEEE
13 years 8 months ago
2004
IEEE
In microarray gene expression data, clusters may hide in subspaces. Traditional clustering algorithms that make use of similarity measurements in the full input space may fail to ...
CSB
2002
IEEE
13 years 9 months ago
2002
IEEE
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
CSB
2003
IEEE
13 years 10 months ago
2003
IEEE
We propose a statistical method for estimating a gene network based on Bayesian networks from microarray gene expression data together with biological knowledge including protein-...