BMCBI
2011
12 years 11 months ago
2011
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
BMCBI
2011
13 years 1 days ago
2011
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
BMCBI
2008
13 years 5 months ago
2008
Background: Health and disease of organisms are reflected in their phenotypes. Often, a genetic component to a disease is discovered only after clearly defining its phenotype. In ...
BMCBI
2008
13 years 5 months ago
2008
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
BMCBI
2010
13 years 5 months ago
2010
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
BMCBI
2010
13 years 5 months ago
2010
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
BMCBI
2010
13 years 5 months ago
2010
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
CRV
2005
IEEE
13 years 10 months ago
2005
IEEE
The problem of elucidating the functional significance of genes is a key challenge of modern science. Solving this problem can lead to fundamental advancements across multiple are...
GECCO
2007
Springer
13 years 11 months ago
2007
Springer
The process of development creates a phenotype from one or more genotypes of an individual through interaction with an environment. The opportunity for development to choose a phe...