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TCBB
2010
91views more  TCBB 2010»
8 years 10 months ago
SCS: Signal, Context, and Structure Features for Genome-Wide Human Promoter Recognition
This paper integrates the signal, context and structure features for genome-wide promoter recognition, which is critical in many DNA sequence analysis tasks. First, CpG islands ar...
Jia Zeng, Xiaoyu Zhao, Xiao-Qin Cao, Hong Yan
BMCBI
2005
106views more  BMCBI 2005»
9 years 3 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
NAR
2008
204views more  NAR 2008»
9 years 3 months ago
ppdb: a plant promoter database
ppdb (http://www.ppdb.gene.nagoya-u.ac.jp) is a plant promoter database that provides promoter annotation of Arabidopsis and rice. The database contains information on promoter st...
Yoshiharu Y. Yamamoto, Junichi Obokata
IJBRA
2006
61views more  IJBRA 2006»
9 years 3 months ago
Finding functional promoter motifs by computational methods: a word of caution
: The standard practice in the analysis of promoters is to select promoter regions of convenient length. This may lead to false results when searching for Transcription Factor Bind...
Rajesh Chowdhary, Limsoon Wong, Vladimir B. Bajic
BMCBI
2007
126views more  BMCBI 2007»
9 years 3 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...
BMCBI
2006
155views more  BMCBI 2006»
9 years 3 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
BMCBI
2006
103views more  BMCBI 2006»
9 years 3 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
BMCBI
2006
108views more  BMCBI 2006»
9 years 3 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2008
123views more  BMCBI 2008»
9 years 3 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...
BMCBI
2008
127views more  BMCBI 2008»
9 years 3 months ago
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides
Background: Promoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II ...
Jian-Yi Yang, Yu Zhou, Zu-Guo Yu, Vo Anh, Li-Qian ...
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