JBCB
2010
12 years 11 months ago
2010
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
TCBB
2010
13 years 2 months ago
2010
—The literature on protein function prediction is currently dominated by works aimed at maximizing predictive accuracy, ignoring the important issues of validation and interpreta...
BMCBI
2007
13 years 4 months ago
2007
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
BMCBI
2008
13 years 4 months ago
2008
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
BMCBI
2010
13 years 4 months ago
2010
Background: The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of diff...
LION
2009
Springer
13 years 11 months ago
2009
Springer
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
RECOMB
2003
Springer
14 years 4 months ago
2003
Springer
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
ICML
2006
IEEE
14 years 5 months ago
2006
IEEE
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...