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NAR
2010
123views more  NAR 2010»
10 years 8 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
APCCM
2009
11 years 2 months ago
Conceptional Modeling and Analysis of Spatio-Temporal Processes in Biomolecular Systems
In life science, deeper understanding of biomolecular systems is acquired by computational modeling and analysis. For the modeling of several kinds of reaction networks, e.g. sign...
Andreas Schäfer, Mathias John
BIOCOMP
2006
11 years 2 months ago
Petri Net Based Model Of The T Cell Receptor Signaling Pathway
Intracellular signaling pathways as well as the interactions and coordination that exist among them are complex and difficult to visualize and understand. Computer-based models of...
Srinidhi Jayasuryan, Anil Bamezai, Vijay Gehlot
SSDBM
2006
IEEE
156views Database» more  SSDBM 2006»
11 years 7 months ago
On Data and Visualization Models for Signaling Pathways
Signaling pathways are chains of interacting proteins, through which the cell converts a (usually) extracellular signal into a biological response. The number of known signaling p...
Nattakarn Ratprasartporn, Ali Cakmak, Gultekin &Ou...
CMSB
2009
Springer
11 years 8 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary diļ¬€erential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
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