BMCBI
2011
12 years 11 months ago
2011
Background: High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow the extensive characterization of Single Nucleotide Polymorp...
BMCBI
2011
12 years 11 months ago
2011
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
BMCBI
2011
13 years 1 days ago
2011
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
SPIRE
2010
Springer
13 years 2 months ago
2010
Springer
Next generation sequencing (NGS) technologies are being applied to many fields of biology, notably to survey the polymorphism across individuals of a species. However, while single...
BIBM
2010
IEEE
13 years 3 months ago
2010
IEEE
The 1000 Genome project has made available a large number of single nucleotide polymorphisms (SNPs) for genome-wide association studies (GWAS). However, the large number of SNPs ha...
BMCBI
2004
13 years 4 months ago
2004
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
BMCBI
2004
13 years 4 months ago
2004
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
BMCBI
2004
13 years 4 months ago
2004
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
BMCBI
2004
13 years 4 months ago
2004
Background: We have compared 38 isolates of the SARS-CoV complete genome. The main goal was twofold: first, to analyze and compare nucleotide sequences and to identify positions o...
BMCBI
2005
13 years 4 months ago
2005
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...