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ICASSP
2011
IEEE
8 years 3 days ago
Uncover cooperative gene regulations by microRNAs and transcription factors in glioblastoma using a nonnegative hybrid factor mo
—Transcriptional regulation by transcription factors (TFs) and microRNAs controls when and how much RNA is created. Due to technical limitations, the protein level expressions of...
Jia Meng, Hung-I Harry Chen, Jianqiu Zhang, Yidong...
NAR
2010
184views more  NAR 2010»
8 years 3 months ago
RegPrecise: a database of curated genomic inferences of transcriptional regulatory interactions in prokaryotes
The RegPrecise database (http://regprecise.lbl.gov) was developed for capturing, visualization and analysis of predicted transcription factor regulons in prokaryotes that were rec...
Pavel S. Novichkov, Olga N. Laikova, Elena S. Novi...
BMCBI
2010
172views more  BMCBI 2010»
8 years 3 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
CISIS
2010
IEEE
8 years 6 months ago
Modeling of Stress-induced Regulatory Cascades Involving Transcription Factor Dimers
Regulatory cascades consisting of stress-induced gene modules and their transcriptional regulators were recently identified and quantitatively modeled using Artificial Neural Netwo...
Maria Manioudaki, Panayiota Poirazi
BIBM
2010
IEEE
161views Bioinformatics» more  BIBM 2010»
8 years 6 months ago
Cis-regulatory module detection using constraint programming
We propose a method for finding CRMs in a set of co-regulated genes. Each CRM consists of a set of binding sites of transcription factors. We wish to find CRMs involving the same t...
Tias Guns, Hong Sun, Kathleen Marchal, Siegfried N...
NAR
2002
89views more  NAR 2002»
8 years 8 months ago
Transcription Regulatory Regions Database (TRRD): its status in 2002
Transcription Regulatory Regions Database (TRRD) is an informational resource containing an integrated description of the gene transcription regulation. An entry of the database c...
Nikolay A. Kolchanov, Elena V. Ignatieva, Elena A....
NAR
2000
117views more  NAR 2000»
8 years 8 months ago
Object-oriented Transcription Factors Database (ooTFD)
ooTFD (object-oriented Transcription Factors Database) is an object-oriented successor to TFD. This database is aimed at capturing information regarding the polypeptide interactio...
David Ghosh
BMCBI
2007
169views more  BMCBI 2007»
8 years 8 months ago
Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana
Background: The central role of transcription factors (TFs) in higher eukaryotes has led to much interest in deciphering transcriptional regulatory interactions. Even in the best ...
Henning Redestig, Daniel Weicht, Joachim Selbig, M...
BMCBI
2005
86views more  BMCBI 2005»
8 years 8 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2007
136views more  BMCBI 2007»
8 years 8 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
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