S3DB core: a framework for RDF generation and management in bioinformatics infrastructures

Background: Biomedical research is set to greatly benefit from the use of semantic web technologies in the design of computational infrastructure. However, beyond well defined research initiatives, substantial issues of data heterogeneity, source distribution, and privacy currently stand in the way towards the personalization of Medicine. Results: A computational framework for bioinformatic infrastructure was designed to deal with the heterogeneous data sources and the sensitive mixture of public and private data that characterizes the biomedical domain. This framework consists of a logical model build with semantic web tools, coupled with a Markov process that propagates user operator states. An accompanying open source prototype was developed to meet a series of applications that range from collaborative multi-institution data acquisition efforts to data analysis applications that need to quickly traverse complex data structures. This report describes the two abstractions underlying...

• Type: Journal
• Year: 2010
• Where: BMCBI
• Authors: Jonas S. Almeida, Helena F. Deus, Wolfgang Maass
• Keywords: BMCBI 2010, Computational Infrastructure, Semantic Web, Semantic Web Technologies