SlowFaster, a user-friendly program for slow-fast analysis and its application on phylogeny of Blastocystis

Background: Slow-fast analysis is a simple and effective method to reduce the influence of substitution saturation, one of the causes of phylogenetic noise and long branch attraction (LBA) artifacts. In several steps of increasing stringency, the slow-fast analysis omits the fastest substituting alignment positions from the analysed dataset and thus increases its signal/noise ratio. Results: Our program SlowFaster automates the process of assessing the substitution rate of the alignment positions and the process of producing new alignments by deleting the saturated positions. Its use is very simple. It goes through the whole process in several steps: data input

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: Martin Kostka, Magdalena Uzlikova, Ivan Cepicka, Jaroslav Flegr
• Keywords: BMCBI 2008, Long Branch Attraction, Positions, Slow-fast Analysis