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BMCBI
2008
181views more  BMCBI 2008»
8 years 8 months ago
Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
BMCBI
2008
149views more  BMCBI 2008»
8 years 8 months ago
MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data
Background: Recent advances in global genomic profiling methodologies have enabled multidimensional characterization of biological systems. Complete analysis of these genomic prof...
Bryan Chi, Ronald J. deLeeuw, Bradley P. Coe, Raym...
BMCBI
2008
214views more  BMCBI 2008»
8 years 8 months ago
Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
Jukka Corander, Pekka Marttinen, Jukka Siré...
BMCBI
2008
166views more  BMCBI 2008»
8 years 8 months ago
QuantPrime - a flexible tool for reliable high-throughput primer design for quantitative PCR
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
Samuel Arvidsson, Miroslaw Kwasniewski, Diego Maur...
BMCBI
2008
191views more  BMCBI 2008»
8 years 8 months ago
BatchPrimer3: A high throughput web application for PCR and sequencing primer design
Background: Microsatellite (simple sequence repeat
Frank M. You, Naxin Huo, Yong Qiang Gu, Ming-Cheng...
BMCBI
2008
128views more  BMCBI 2008»
8 years 10 months ago
In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
Shivashankar H. Nagaraj, Robin B. Gasser, Alasdair...
BMCBI
2008
184views more  BMCBI 2008»
8 years 10 months ago
"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI
Background: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecule...
Pornpat Nikamanon, Elroy Pun, Wayne Chou, Marek D....
BMCBI
2008
132views more  BMCBI 2008»
8 years 10 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...
BMCBI
2008
149views more  BMCBI 2008»
8 years 10 months ago
All-paths graph kernel for protein-protein interaction extraction with evaluation of cross-corpus learning
Background: Automated extraction of protein-protein interactions (PPI) is an important and widely studied task in biomedical text mining. We propose a graph kernel based approach ...
Antti Airola, Sampo Pyysalo, Jari Björne, Tap...
BMCBI
2008
158views more  BMCBI 2008»
8 years 10 months ago
VarDetect: a nucleotide sequence variation exploratory tool
Background: Single nucleotide polymorphisms (SNPs) are the most commonly studied units of genetic variation. The discovery of such variation may help to identify causative gene mu...
Chumpol Ngamphiw, Supasak Kulawonganunchai, Anunch...
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