The Autoimmune Disease Database: a dynamically compiled literature-derived database

Background: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically distinct diseases, among them systemic lupus erythematosus and rheumatoid arthritis, are classified as autoimmune diseases. Although their etiology is unclear these diseases share certain similarities at the molecular level i.e. susceptibility regions on the chromosomes or the involvement of common genes. To gain an overview of these related diseases it is not feasible to do a literary review but it requires methods of automated analyses of the more than 500,000 Medline documents related to autoimmune disorders. Results: In this paper we present the first version of the Autoimmune Disease Database which to our knowledge is the first comprehensive literature-based database covering all known or suspected autoimmune diseases. This dynamically compiled database allows researchers to link autoimmune diseases to the c...

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Thomas Karopka, Juliane Fluck, Heinz-Theodor Mevissen, Änne Glass
• Keywords: Autoimmune Disease Database, Autoimmune Diseases, BMCBI 2006, Distinct Diseases