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2010
IEEE

Digital Microfluidic Biochips: A Vision for Functional Diversity and More than Moore

12 years 3 months ago
Digital Microfluidic Biochips: A Vision for Functional Diversity and More than Moore
Abstract—Microfluidics-based biochips are revolutionizing highthroughput sequencing, parallel immunoassays, clinical diagnostics, and drug discovery. These devices enable the precise control of nanoliter volumes of biochemical samples and reagents. Compared to conventional laboratory procedures, which are cumbersome and expensive, miniaturized biochips offer the advantages of higher sensitivity, lower cost due to smaller sample and reagent volumes, system integration, and less likelihood of human error. This embedded tutorial paper provides an overview of droplet-based “digital” microfluidic biochips. It describes emerging computer-aided design (CAD) tools for the automated synthesis and optimization of biochips from bioassay protocols. Recent advances in fluidic-operation scheduling, module placement, droplet routing, pin-constrained chip design, and testing are presented.
Krishnendu Chakrabarty
Added 16 Aug 2010
Updated 16 Aug 2010
Type Conference
Year 2010
Where VLSID
Authors Krishnendu Chakrabarty
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