inGeno - an integrated genome and ortholog viewer for improved genome to genome comparisons

Background: Systematic genome comparisons are an important tool to reveal gene functions, pathogenic features, metabolic pathways and genome evolution in the era of post-genomics. Furthermore, such comparisons provide important clues for vaccines and drug development. Existing genome comparison software often lacks accurate information on orthologs, the function of similar genes identified and genome-wide reports and lists on specific functions. All these features and further analyses are provided here in the context of a modular software tool "inGeno" written in Java with Biojava subroutines. Results: InGeno provides a user-friendly interactive visualization platform for sequence comparisons (comprehensive reciprocal protein

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Chunguang Liang, Thomas Dandekar
• Keywords: BMCBI 2006, Genome Comparison, Genomes, Systematic Genome Comparisons