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BMCBI
2011
8 years 2 months ago
Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies
Background: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improve...
Joshua Wetzel, Carl Kingsford, Mihai Pop
BMCBI
2011
8 years 3 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
BMCBI
2011
8 years 3 months ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
RECOMB
2010
Springer
8 years 6 months ago
A New Genomic Evolutionary Model for Rearrangements, Duplications, and Losses That Applies across Eukaryotes and Prokaryotes
Background: Genomic rearrangements have been studied since the beginnings of modern genetics and models for such rearrangements have been the subject of many papers over the last ...
Yu Lin, Bernard M. E. Moret
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
8 years 6 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
8 years 6 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...
IJBRA
2010
121views more  IJBRA 2010»
8 years 6 months ago
Mining Cytochrome b561 proteins from plant genomes
—Cytochrome b561 (Cyt-b561) proteins play important functions in plants such as anti-toxin defense reactions, growth and development, and prevention of damage to plants from exce...
Stephen O. Opiyo, Etsuko N. Moriyama
AIPS
2010
8 years 7 months ago
Genome Rearrangement and Planning: Revisited
Evolutionary trees of species can be reconstructed by pairwise comparison of their entire genomes. Such a comparison can be quantified by determining the number of events that ch...
Tansel Uras, Esra Erdem
NAR
2007
115views more  NAR 2007»
8 years 7 months ago
DroSpeGe: rapid access database for new Drosophila species genomes
The Drosophila species comparative genome database DroSpeGe (http://insects.eugenes.org/ DroSpeGe/) provides genome researchers with rapid, usable access to 12 new and old Drosoph...
Donald G. Gilbert
NAR
2002
138views more  NAR 2002»
8 years 8 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...
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