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BMCBI
2006

INTEGRATOR: interactive graphical search of large protein interactomes over the Web

9 years 12 months ago
INTEGRATOR: interactive graphical search of large protein interactomes over the Web
Background: The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces are of exponential complexity. This poses special challenges for storing, searching, and navigating this data efficiently. Moreover, development of effective web interfaces has been difficult. Results: We present Integrator, a web-integrated graphical search tool for protein-protein interaction networks across 50+ genomes. Conclusion: Integrator provides single and multiple protein searches of the Bioverse database containing experimentally-derived and predicted protein-protein interactions. The interface provides animated local network views, rapid subgraph manipulation, and cross-referencing of functional annotations. Integrator is available at http://bioverse.compbio.washington.edu/ integrator. Background High-throughput technologies that monitor cellular components on a large scale are becoming ubiquitou...
Aaron N. Chang, Jason McDermott, Zachary Frazier,
Added 10 Dec 2010
Updated 10 Dec 2010
Type Journal
Year 2006
Where BMCBI
Authors Aaron N. Chang, Jason McDermott, Zachary Frazier, Michal Guerquin, Ram Samudrala
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