The Mathematical Model of Subtractive Hybridization and Its Practical Application

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A novel theory of subtractive hybridization including (or based on) the kinetic model of this process was proposed. A computer program modeling the process of subtraction wasdeveloped. Basing on the theory, a novel method of subtractive hybridization was proposed allowing routine comparison of genomes and products of genome expression. Themethodwasapplied to studies of the genetic mechanismsof embryogenesis, regeneration, cell differentiation and tumortransformation.

Olga D. Ermolaeva, Sergey A. Lukyanov, Eugene D. S

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Computational Biology | Genetic Mechanismsof Embryogenesis | ISMB 1996 | Kinetic Model | Subtractive Hybridization |

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Added	02 Nov 2010
Updated	02 Nov 2010
Type	Conference
Year	1996
Where	ISMB
Authors	Olga D. Ermolaeva, Sergey A. Lukyanov, Eugene D. Sverdlov

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The Mathematical Model of Subtractive Hybridization and Its Practical Application

Computational Biology | Genetic Mechanismsof Embryogenesis | ISMB 1996 | Kinetic Model | Subtractive Hybridization |

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