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2010
IEEE

Multi Level Clustering of Phylogenetic Profiles

9 years 6 days ago
Multi Level Clustering of Phylogenetic Profiles
The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to infer gene function. However, the availability of several fully sequenced genomes has enabled alternative approaches, such as phylogenetic profiles. Phylogenetic profiles are vectors which indicate the presence or absence of a gene in other genomes. The main concept of phylogenetic profiles is that proteins participating in a common structural complex or metabolic pathway are likely to evolve in a correlated fashion. In this paper, a multi level clustering algorithm of phylogenetic profiles is presented, which aims to detect inter- and intragenome gene clusters. Keywords- Algorithm; Clustering; Phylogenetic profiles
Fotis E. Psomopoulos, Pericles A. Mitkas
Added 08 Nov 2010
Updated 08 Nov 2010
Type Conference
Year 2010
Where BIBE
Authors Fotis E. Psomopoulos, Pericles A. Mitkas
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