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2009
IEEE

Multi-Modal Registration of Embryonic Images for In Vitro Fertilization

9 years 1 months ago
Multi-Modal Registration of Embryonic Images for In Vitro Fertilization
This paper presents a robust and fully automated registration algorithm for alignment of embryonic images taken by Optical Quadrature Microscopy (OQM) and Differential Interference Contrast (DIC) Microscopy. Registration of such images allows recognition of distinguishing features of viable embryos, such as growth rate, to reduce multiple births from In Vitro Fertilization. OQM is an optical interferometer whereas the DIC images gradient of the phase. Due to the very different nature of the image formation, the interior of the embryo appears substantially different if not totally uncorrelated between different modalities. We present an algorithm which extracts and aligns the silhouettes of the embryo—the most invariant features between different modalities. The algorithm is tested with 28 image pairs taken from different embryos at various development stages. The success rate is 85.7% if only affine transformation is adopted, and 96% if similarity transformation is allowed for embr...
Chia-Ling Tsai, Su-Ching Liang, William Warger, Ch
Added 18 May 2010
Updated 18 May 2010
Type Conference
Year 2009
Where BIBE
Authors Chia-Ling Tsai, Su-Ching Liang, William Warger, Charles DiMarzio
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