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JCC
2011

NUPACK: Analysis and design of nucleic acid systems

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NUPACK: Analysis and design of nucleic acid systems
: The Nucleic Acid Package (NUPACK) is a growing software suite for the analysis and design of nucleic acid systems. The NUPACK web server (http://www.nupack.org) currently enables: • Analysis: thermodynamic analysis of dilute solutions of interacting nucleic acid strands. • Design: sequence design for complexes of nucleic acid strands intended to adopt a target secondary structure at equilibrium. • Utilities: evaluation, display, and annotation of equilibrium properties of a complex of nucleic acid strands. NUPACK algorithms are formulated in terms of nucleic acid secondary structure. In most cases, pseudoknots are excluded from the structural ensemble. © 2010 Wiley Periodicals, Inc. J Comput Chem 32: 170–173, 2011 Key words: RNA; DNA; complexes; concentrations; sequence design
Joseph N. Zadeh, Conrad Steenberg, Justin S. Bois,
Added 14 May 2011
Updated 14 May 2011
Type Journal
Year 2011
Where JCC
Authors Joseph N. Zadeh, Conrad Steenberg, Justin S. Bois, Brian R. Wolfe, Marshall B. Pierce, Asif R. Khan, Robert M. Dirks, Niles A. Pierce
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