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RECOMB
1997
Springer

Progressive multiple alignment with constraints

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Progressive multiple alignment with constraints
A progressive alignment algorithm produces a multi-alignment of a set of sequences by repeatedly aligning pairs of sequences and/or previously generated alignments. We describe a method for guaranteeing that the alignment generated by a progressivealignment strategy satisfies a user-specified collection of constraints about where certain sequence positions should appear relative to others. Given a collection of ¢ constraints over £ sequences whose total length is ¤ , our algorithm takes ¥ ¦ £ ¦ ¤ § ¨ £ ¢ © © time. An alignment of the  -like globin gene clusters of several mammals illustrates the practicality of the method. Key words: Multiplesequence alignment, constrainedalignment, dynamic programming
Gene Myers, Sanford Selznick, Zheng Zhang 0004, We
Added 08 Aug 2010
Updated 08 Aug 2010
Type Conference
Year 1997
Where RECOMB
Authors Gene Myers, Sanford Selznick, Zheng Zhang 0004, Webb Miller
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