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2007

TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT method

10 years 23 days ago
TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT method
TOPOFIT-DB (T-DB) is a public web-based database of protein structural alignments based on the TOPOFIT method, providing a comprehensive resource for comparative analysis of protein structure families. The TOPOFIT method is based on the discovery of a saturation point on the alignment curve (topomax point) which presents an ability to objectively identify a border between common and variable parts in a protein structural family, providing additional insight into protein comparison and functional annotation. TOPOFIT also effectively detects non-sequential relations between protein structures. T-DB provides users with the convenient ability to retrieve and analyze structural neighbors for a protein; do one-to-all calculation of a user provided structure against the entire current PDB release with T-Server, and pair-wise comparison using the TOPOFIT method through the T-Pair web page. All outputs are reported in various web-based tables and graphics, with automated viewing of the structu...
Chesley M. Leslin, Alexej Abyzov, Valentin A. Ilyi
Added 27 Dec 2010
Updated 27 Dec 2010
Type Journal
Year 2007
Where NAR
Authors Chesley M. Leslin, Alexej Abyzov, Valentin A. Ilyin
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