Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...