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» A Geometric Representation of Protein Sequences
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BIBM
2007
IEEE
13 years 11 months ago
A Geometric Representation of Protein Sequences
The amino acid sequence of a protein is the key to understanding its structure and ultimately its function in the cell. This paper addresses the fundamental issue of encoding amin...
Shengyin Gu, Olivier Poch, Bernd Hamann, Patrice K...
RECOMB
1999
Springer
13 years 9 months ago
Fast detection of common geometric substructure in proteins
We consider the problem of identifying common three-dimensional substructures between proteins. Our method is based on comparing the shape of the α-carbon backbone structures of ...
L. Paul Chew, Daniel P. Huttenlocher, Klara Kedem,...
CORR
2006
Springer
121views Education» more  CORR 2006»
13 years 4 months ago
Number sequence representation of protein structures based on the second derivative of a folded tetrahedron sequence
A protein is a sequence of amino-acids of length typically less than 1, 000, where there are 20 kinds of amino-acids. In nature, each protein is folded into a well-defined three-d...
Naoto Morikawa
BIBE
2007
IEEE
152views Bioinformatics» more  BIBE 2007»
13 years 4 months ago
SBLAST: Structural Basic Local Alignment Searching Tools using Geometric Hashing
While much research has been done on finding similarities between protein sequences, there has not been the same progress on finding similarities between protein structures. Here ...
Tom Milledge, Gaolin Zheng, Tim Mullins, Giri Nara...
BMCBI
2005
119views more  BMCBI 2005»
13 years 4 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona