Global likelihood maximization is an important aspect of many statistical analyses. Often the likelihood function is highly multi-extremal. This presents a significant challenge t...
: Accurate reconstruction of phylogenetic trees very often involves solving hard optimization problems, particularly the maximum parsimony (MP) and maximum likelihood (ML) problems...
Cristian Coarfa, Yuri Dotsenko, John M. Mellor-Cru...
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
David Burstein, Igor Ulitsky, Tamir Tuller, Benny ...
Probabilistic graphical models such as Bayesian Networks have been increasingly applied to many computer vision problems. Accuracy of inferences in such models depends on the quali...