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RECOMB
2005
Springer
14 years 5 months ago
Predicting Transcription Factor Binding Sites Using Structural Knowledge
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...
Tommy Kaplan, Nir Friedman, Hanah Margalit
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
13 years 10 months ago
Discriminative Discovery of Transcription Factor Binding Sites from Location Data
Motivation: The availability of genome-wide location analyses based on chromatin immunoprecipitation (ChIP) data gives a new insight for in silico analysis of transcriptional regu...
Yuji Kawada, Yasubumi Sakakibara
RECOMB
2004
Springer
14 years 5 months ago
A discriminative model for identifying spatial cis-regulatory modules
Transcriptional regulation is mediated by the coordinated binding of transcription factors to the upstream regions of genes. In higher eukaryotes, the binding sites of cooperating...
Eran Segal, Roded Sharan
RECOMB
2003
Springer
14 years 5 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
JCB
2002
87views more  JCB 2002»
13 years 4 months ago
The Repetitive Sequence Database and Mining Putative Regulatory Elements in Gene Promoter Regions
At least 43% of the human genome is occupied by repetitive elements. Moreover, around 51% of the rice genome is occupied by repetitive elements. The analysis of repetitive element...
Jorng-Tzong Horng, Hsien-Da Huang, Ming-Hui Jin, L...