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IJCBDD
2011
112views more  IJCBDD 2011»
12 years 11 months ago
A novel network model identified a 13-gene lung cancer prognostic signature
: This study presents a novel network methodology to identify prognostic gene signatures. Implication networks based on prediction logic are used to construct genome-wide coexpress...
Nancy Lan Guo, Ying-Wooi Wan, Swetha Bose, James D...
BCB
2010
127views Bioinformatics» more  BCB 2010»
12 years 11 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
13 years 2 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
13 years 9 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
BMCBI
2010
95views more  BMCBI 2010»
13 years 4 months ago
Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
Esteban Czwan, Benedikt Brors, David Kipling