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» A survey of DNA motif finding algorithms
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BMCBI
2007
247views more  BMCBI 2007»
13 years 4 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2007
190views more  BMCBI 2007»
13 years 4 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
RECOMB
2005
Springer
14 years 4 months ago
Improved Pattern-Driven Algorithms for Motif Finding in DNA Sequences
Abstract. In order to guarantee that the optimal motif is found, traditional pattern-driven approaches perform an exhaustive search over all candidate motifs of length l. We develo...
Sing-Hoi Sze, Xiaoyan Zhao
RECOMB
2002
Springer
14 years 4 months ago
Finding motifs in the twilight zone
We introduce the notion of a multiprofile and use it for finding subtle motifs in DNA sequences. Multiprofiles generalize the notion of a profile and allow one to detect subtle co...
Uri Keich, Pavel A. Pevzner
APBC
2008
231views Bioinformatics» more  APBC 2008»
13 years 6 months ago
Optimal Algorithm for Finding DNA Motifs with Nucleotide Adjacent Dependency
: Finding motifs and the corresponding binding sites is a critical and challenging problem in studying the process of gene expression. String and matrix representations are two pop...
Francis Y. L. Chin, Henry C. M. Leung, Man-Hung Si...