6 search results - page 1 / 2 » Acceleration of Covariance Models for Non-coding RNA Search |
BIOCOMP
2006
13 years 6 months ago
2006
Stochastic context-free grammar (SCFG) based models for non-coding RNA (ncRNA) gene searches are much more powerful than regular grammar based models due to the ability to model in...
ISMB
2004
13 years 6 months ago
2004
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
CSB
2005
IEEE
13 years 10 months ago
2005
IEEE
Searching genomes for RNA secondary structure with computational methods has become an important approach to the annotation of non-coding RNAs. However, due to the lack of effici...
BMCBI
2002
13 years 4 months ago
2002
Background: Covariance models (CMs) are probabilistic models of RNA secondary structure, analogous to profile hidden Markov models of linear sequence. The dynamic programming algo...
BMCBI
2008
13 years 4 months ago
2008
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...