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BMCBI
2006
172views more  BMCBI 2006»
13 years 5 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BIBE
2007
IEEE
147views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
A New Alignment-Independent Algorithm for Clustering Protein Sequences
—The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important, the challenge is to identify subfamilies of evolut...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski
JCB
2002
74views more  JCB 2002»
13 years 5 months ago
Using Substitution Matrices to Estimate Probability Distributions for Biological Sequences
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
Eleazar Eskin, William Stafford Noble, Yoram Singe...
BMCBI
2006
172views more  BMCBI 2006»
13 years 5 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
ISMB
2001
13 years 6 months ago
Using mixtures of common ancestors for estimating the probabilities of discrete events in biological sequences
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
Eleazar Eskin, William Noble Grundy, Yoram Singer