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ISMB
1993
13 years 6 months ago
Identification of Localized and Distributed Bottlenecks in Metabolic Pathways
The usual thermodynamicevaluation, based solely on the Standard Gibbs Energyof reaction, does not take into account the permissible ranges of concentrations of metabolites, and it...
Michael L. Mavrovouniotis
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
13 years 10 months ago
A Pivoting Algorithm for Metabolic Networks in the Presence of Thermodynamic Constraints
A linear programming algorithm is presented to constructively compute thermodynamically feasible fluxes and change in chemical potentials of reactions for a metabolic network. It...
R. Nigam, S. Liang
CORR
2008
Springer
116views Education» more  CORR 2008»
13 years 4 months ago
A statistical mechanical interpretation of algorithmic information theory
Abstract. We develop a statistical mechanical interpretation of algorithmic information theory by introducing the notion of thermodynamic quantities, such as free energy, energy, s...
Kohtaro Tadaki
CORR
2010
Springer
154views Education» more  CORR 2010»
13 years 4 months ago
Algorithmic Thermodynamics
Algorithmic entropy can be seen as a special case of entropy as studied in statistical mechanics. This viewpoint allows us to apply many techniques developed for use in thermodyna...
John C. Baez, Mike Stay
BMCBI
2004
151views more  BMCBI 2004»
13 years 4 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich