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CEC
2007
IEEE
13 years 11 months ago
A co-evolutionary framework for regulatory motif discovery
Abstract— In previous work, we have shown how an evolutionary algorithm with a clustered population can be used to concurrently discover multiple regulatory motifs present within...
Michael A. Lones, Andy M. Tyrrell
IJDMB
2006
90views more  IJDMB 2006»
13 years 5 months ago
An efficient motif discovery algorithm with unknown motif length and number of binding sites
: Most motif discovery algorithms from DNA sequences require the motif's length as input. Styczynski et al. introduced the Extended (l,d)-Motif Problem (EMP) where the motif&#...
Henry C. M. Leung, Francis Y. L. Chin
BMCBI
2010
134views more  BMCBI 2010»
13 years 5 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BIBM
2009
IEEE
156views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
Bayesian Classifier for Anchored Protein Sorting Discovery
—A typical cell has a size of only 10 µm while it contains about a billion proteins. Transportation of these proteins from their synthesis sites to their target locations within...
Fan Zhang, Jianjun Hu
BMCBI
2006
87views more  BMCBI 2006»
13 years 5 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen