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RECOMB
2005
Springer
14 years 5 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
BIOINFORMATICS
2012
11 years 7 months ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
BMCBI
2004
146views more  BMCBI 2004»
13 years 4 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2008
100views more  BMCBI 2008»
13 years 4 months ago
Extracting transcription factor binding sites from unaligned gene sequences with statistical models
Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hyb...
Chung-Chin Lu, Wei-Hao Yuan, Te-Ming Chen
JIB
2006
78views more  JIB 2006»
13 years 4 months ago
Prediction of transcription factor binding to DNA using rule induction methods
In this study, we seek to develop a predictive model for finding the strength of binding between a particular transcription factor (TF) variant and a particular DNA target variant...
Mikael Huss, Karin Nordström