The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. In recent years there has been a growing interest in using high ...
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Abstract. Computational analysis of mass spectrometric (MS) proteomic data from sera is of potential relevance for diagnosis, prognosis, choice of therapy, and study of disease act...
Elena Marchiori, Connie R. Jimenez, Mikkel West-Ni...
Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detectio...
Werner W. V. B. Van Belle, Nina N. A. Anensen, Ing...