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BMCBI
2008
114views more  BMCBI 2008»
13 years 5 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
IPPS
2008
IEEE
13 years 11 months ago
Parallel mining of closed quasi-cliques
Graph structure can model the relationships among a set of objects. Mining quasi-clique patterns from large dense graph data makes sense with respect to both statistic and applica...
Yuzhou Zhang, Jianyong Wang, Zhiping Zeng, Lizhu Z...
BMCBI
2010
117views more  BMCBI 2010»
13 years 5 months ago
Properties and identification of antibiotic drug targets
Background: We analysed 48 non-redundant antibiotic target proteins from all bacteria, 22 antibiotic target proteins from E. coli only and 4243 non-drug targets from E. coli to id...
Tala Bakheet, Andrew J. Doig
ISMB
2008
13 years 7 months ago
Classification of arrayCGH data using fused SVM
Motivation: Array-based comparative genomic hybridization (arrayCGH) has recently become a popular tool to identify DNA copy number variations along the genome. These profiles are...
Franck Rapaport, Emmanuel Barillot, Jean-Philippe ...
BMCBI
2007
157views more  BMCBI 2007»
13 years 5 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...