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» Calling SNPs without a reference sequence
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DEXAW
2003
IEEE
131views Database» more  DEXAW 2003»
13 years 10 months ago
Having a BLAST: Analyzing Gene Sequence Data with BlastQuest
An essential problem for biologists is the processing and evaluation of BLAST results. We advocate the deployment of database technology and describe a userdriven tool, called Bla...
William G. Farmerie, Joachim Hammer, Li Liu, Marku...
RECOMB
2012
Springer
11 years 7 months ago
Estimating the Accuracy of Multiple Alignments and its Use in Parameter Advising
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
Dan F. DeBlasio, Travis J. Wheeler, John D. Kececi...
CIBCB
2006
IEEE
13 years 11 months ago
Machine Learning in Basecalling Decoding Trace Peak Behaviour
— DNA sequence basecalling is commonly regarded as a solved problem, despite significant error rates being reflected in inaccuracies in databases and genome annotations. These er...
David Thornley, Stavros Petridis
WABI
2009
Springer
132views Bioinformatics» more  WABI 2009»
13 years 11 months ago
mpscan: Fast Localisation of Multiple Reads in Genomes
Abstract. With Next Generation Sequencers, sequence based transcriptomic or epigenomic assays yield millions of short sequence reads that need to be mapped back on a reference geno...
Eric Rivals, Leena Salmela, Petteri Kiiskinen, Pet...
EACL
1993
ACL Anthology
13 years 6 months ago
A Computational Treatment of Sentence-Final 'then'
We describe a computational system which parses discourses consisting of sequences of simple sentences. These contain a range of temporal constructions, including time adverbials,...
Sheila Glasbey