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» Case Studies in Protein Structure Prediction with Real-value...
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2004
Springer
13 years 10 months ago
Two-Step Genetic Programming for Optimization of RNA Common-Structure
We present an algorithm for identifying putative non-coding RNA (ncRNA) using an RCSG (RNA Common-Structural Grammar) and show the effectiveness of the algorithm. The algorithm con...
Jin-Wu Nam, Je-Gun Joung, Y. S. Ahn, Byoung-Tak Zh...
BMCBI
2008
124views more  BMCBI 2008»
13 years 5 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2010
116views more  BMCBI 2010»
13 years 5 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
EC
2006
121views ECommerce» more  EC 2006»
13 years 5 months ago
A Study of Structural and Parametric Learning in XCS
The performance of a learning classifier system is due to its two main components. First, it evolves new structures by generating new rules in a genetic process; second, it adjust...
Tim Kovacs, Manfred Kerber
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 12 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...