Abstract. Haplotype inference has relevant biological applications, and represents a challenging computational problem. Among others, pure parsimony provides a viable modeling appr...
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Abstract. Despite the desirable information contained in complex pedigree datasets, analysis methods struggle to efficiently process these datasets. The attractiveness of pedigree ...
Bonnie Kirkpatrick, Javier Rosa, Eran Halperin, Ri...
The within-species genetic variation due to recombinations leads to a mosaic-like structure of DNA. This structure can be modeled, e.g. by parsing sample sequences of current DNA w...
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...
Bonnie Kirkpatrick, Carlos Santos Armendariz, Rich...