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» Combining haplotypers
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CPAIOR
2008
Springer
13 years 6 months ago
Efficient Haplotype Inference with Combined CP and OR Techniques
Abstract. Haplotype inference has relevant biological applications, and represents a challenging computational problem. Among others, pure parsimony provides a viable modeling appr...
Ana Graça, João Marques-Silva, In&ec...
JCB
2006
123views more  JCB 2006»
13 years 4 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
RECOMB
2009
Springer
14 years 5 months ago
Haplotype Inference in Complex Pedigrees
Abstract. Despite the desirable information contained in complex pedigree datasets, analysis methods struggle to efficiently process these datasets. The attractiveness of pedigree ...
Bonnie Kirkpatrick, Javier Rosa, Eran Halperin, Ri...
WABI
2007
Springer
110views Bioinformatics» more  WABI 2007»
13 years 11 months ago
Haplotype Inference Via Hierarchical Genotype Parsing
The within-species genetic variation due to recombinations leads to a mosaic-like structure of DNA. This structure can be modeled, e.g. by parsing sample sequences of current DNA w...
Pasi Rastas, Esko Ukkonen
BIOINFORMATICS
2007
90views more  BIOINFORMATICS 2007»
13 years 4 months ago
HAPLOPOOL: improving haplotype frequency estimation through DNA pools and phylogenetic modeling
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...
Bonnie Kirkpatrick, Carlos Santos Armendariz, Rich...