Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...