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» Compositional Binding in Network Domains
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NAR
2010
194views more  NAR 2010»
13 years 6 days ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
BMCBI
2007
107views more  BMCBI 2007»
13 years 5 months ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
BIOCOMP
2009
13 years 6 months ago
Evolution of Domain Compositions in the Metabolic Networks of Human and Escherichia Coli
It is widely recognized that complexity of metabolic networks arises from duplication, recruitment and recombination of enzyme protein domains. However, variations of the domain ev...
Chen-Hsiang Yeang, Nils Baas
BMEI
2009
IEEE
13 years 6 months ago
Analysis of the Bipartite Networks of Domain Compositions and Metabolic Reactions
It is widely accepted that complexity of biological systems arises from combinations of common subunits. In this work we investigate the combinatorial patterns of protein domains ...
Chen-Hsiang Yeang
BMCBI
2010
82views more  BMCBI 2010»
13 years 5 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...