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» Computationally Optimised DNA Assembly of synthetic genes
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BMCBI
2010
176views more  BMCBI 2010»
13 years 5 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2006
86views more  BMCBI 2006»
13 years 5 months ago
MCALIGN2: Faster, accurate global pairwise alignment of non-coding DNA sequences based on explicit models of indel evolution
Background: Non-coding DNA sequences comprise a very large proportion of the total genomic content of mammals, most other vertebrates, many invertebrates, and most plants. Unravel...
Jun Wang, Peter D. Keightley, Toby Johnson
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
14 years 4 days ago
On the Design of Oligos for Gene Synthesis
— Methods for reliable synthesis of long genes offer great promise for protein synthesis via expression of synthetic genes, with applications to improved analysis of protein stru...
Chris Thachuk, Anne Condon
BMCBI
2008
220views more  BMCBI 2008»
13 years 5 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
BICOB
2009
Springer
14 years 11 days ago
Assembly of Large Genomes from Paired Short Reads
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
Benjamin G. Jackson, Patrick S. Schnable, Srinivas...